Southwest Seasoning Spice Mix

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Southwest seasoning is a smoky, savory spice blend made with chili powder, cumin, coriander, smoked paprika, and garlic. This homemade seasoning mix takes just 5 minutes to make and is perfect for chicken, roasted vegetables, sweet potatoes, tacos, and sheet pan dinners.

Southwest Seasoning Mix – Easy homemade pantry staple, this spice mix is great on grilled vegetables, grilled chicken, roasted sweet potatoes, my slowcooker salsa chicken. PiperCooks

Recipe Testing

I’ve been making this southwest seasoning mix for years and use it regularly on chicken, roasted sweet potatoes, vegetables, and taco-inspired meals. During testing, I found that smoked paprika was the ingredient that made the biggest difference, adding a subtle smoky flavor that helps distinguish this blend from taco seasoning.

I also prefer keeping this seasoning salt-free. This allows me to season each recipe individually rather than adding salt to the spice blend itself. It’s especially useful when using the seasoning on different proteins and vegetables since each recipe may require a different amount of salt.

The cayenne pepper adds a mild heat level, but it’s easy to adjust. For a milder seasoning, reduce or omit the cayenne. For a spicier blend, add an extra pinch.

Southwest Seasoning Mix – Easy homemade pantry staple, this spice mix is great on grilled vegetables, grilled chicken, roasted sweet potatoes, my slowcooker salsa chicken. PiperCooks

Ingredients

See the recipe card for exact amounts.

  • Chili Powder: The foundation of this southwest seasoning blend. Chili powder adds earthy flavor, mild heat, and the rich red color associated with southwest-inspired recipes.
  • Ground Cumin: Adds a warm, earthy flavor that pairs well with grilled meats, beans, and vegetables.
  • Ground Coriander: Coriander provides a subtle citrusy flavor that helps brighten the blend and balance the smokier spices.
  • Dried Oregano: Adds an herbal note that complements the chili powder and cumin.
  • Garlic Powder: Brings savory flavor throughout the seasoning mix without requiring fresh garlic.
  • Onion Powder: Adds sweetness and depth that helps round out the overall flavor.
  • Smoked Paprika: One of my favorite ingredients in this blend. Smoked paprika adds a rich smoky flavor that’s especially delicious on grilled chicken, roasted vegetables, and sweet potatoes.
  • Cayenne Pepper: Provides a touch of heat. Adjust the amount to suit your preferences or leave it out entirely for a milder seasoning mix.
Southwest Seasoning Mix – Easy homemade pantry staple, this spice mix is great on grilled vegetables, grilled chicken, roasted sweet potatoes, my slowcooker salsa chicken. PiperCooks

Tips for Making Southwest Seasoning

  • Use fresh spices for the best flavor. Older spices lose potency over time.
  • Whisk the spices thoroughly to ensure even distribution.
  • Double or triple the recipe if you use southwest seasoning regularly.
  • Label the jar with the name and date so you know when it was made.
  • Adjust the cayenne pepper to control the heat level.
  • Keep the blend salt-free and season individual dishes separately for better control.
Southwest Seasoning Mix – Easy homemade pantry staple, this spice mix is great on grilled vegetables, grilled chicken, roasted sweet potatoes, my slowcooker salsa chicken. PiperCooks

How to Make Southwest Seasoning

  1. Measure all spices into a small bowl.
  2. Whisk until the mixture is evenly combined and no streaks remain.
  3. Transfer the seasoning mix to a clean jar or airtight container.
  4. Seal tightly and store in a cool, dark pantry until ready to use.

Storage

Store southwest seasoning in an airtight container or small mason jar in a cool, dark pantry.

For the best flavor, use within 6 months, although the blend will remain safe to use longer if stored properly. Homemade seasoning mixes gradually lose potency over time, so replacing them regularly helps maintain the strongest flavor.

What to Use Southwest Seasoning On

FAQs

What is southwest seasoning made of?

Southwest seasoning is typically made from chili powder, cumin, coriander, oregano, garlic powder, onion powder, paprika, and a small amount of cayenne pepper for heat.

How long does homemade southwest seasoning last?

When stored in an airtight container in a cool, dark place, homemade southwest seasoning is best used within 6 months for optional freshness but can still be used after that.

More Seasoning Mix Recipes

If you’ve made this Southwest Seasoning Mix recipe or another recipe on Pipercooks, I’d love it if you’d leave a comment with a recipe rating. I want to know how you enjoyed it, and ratings help other people know that the recipe is worth trying.

A jar with an orange seasoning mix.
5 from 1 vote

Southwest Seasoning Mix

Prep Time: 5 minutes
Cook Time: 0 minutes
Total Time: 5 minutes
Servings: 5 tbsp
Homemade spice mixes are an easy do-it-yourself pantry item – this one is great on chicken, sweet potatoes, and vegetables and lets you control the salt.

Ingredients
  

Instructions

  • Mix all spices together.
  • Store in a jar with a lid.

Notes

Store in a cool dark place for up to 6 months.

Nutrition

Calories: 21kcal | Carbohydrates: 4g | Protein: 1g | Fat: 1g | Fiber: 2g | Sugar: 0.4g | Calcium: 35mg | Iron: 2mg

Nutritional information is an estimate. Values vary based on products used. Read our full Nutrition Disclaimer.

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A jar with an orange seasoning mix.

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